Heroin Detox
Heroin addiction is one of the most difficult addictions to overcome. The heroin abuser’s nervous system becomes accustomed to accommodating chronic exposure to the drug, which is an opioid.
Francis Moraes wrote in The Little Book of Heroin, that there are three important brain chemicals or neurotransmitters that relate to heroin. First, dopamine helps to control human appetites for both food and sex. If a person has large quantities of dopamine they are considered out-going and exuberant. Persons who suffer with Parkinson’s disease and depression are said to have too little dopamine.
On the other hand, people suffering from schizophrenia have too much. Heroin causes a release of dopamine. Second, norepinephrin controls the sympathetic nervous system: nerves of the body that cannot be voluntarily controlled. This neurotransmitter stabilizes blood pressure so that it does not get too low.
The brain’s release of norepinephrin stimulates the fight or flight response. But heroin suppresses the middle part of the brain called the locus coeruleus and therefore provides the user with feelings of safety and contentment. Third, endorphines, which are morphine-like chemicals, used by the body to modulate mood, promote pleasure, and manage reactions to stress.2 These three chemicals are exaggerated or heightened by heroin use.
There are several forms of heroin detoxification including opioid agonist drugs, such as methadone, levo-alpha-acetylmethadol (LAAM), or Buprenorphine; Clonidine, which blocks some withdrawal symptoms; ultra-rapid opioid detox under anesthesia; and an experimental method using the drug lofexidine. Opioid agonist drugs act like heroin but do not provide the same high and are administered in gradually decreasing doses.
